cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
Blog Article
2009, discovery of a different phenotype for germs in slim nanofluidic slits; and 1st detection of community protein constructions alongside DNA employing stable-condition nanopores
You will help our creator matching technique! Should you see any publications incorrectly attributed to this creator, remember to sign in and mark matches as accurate or incorrect.
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
Given that 2000, Dekker has shifted the most crucial target of his do the job in the direction of biophysics the place he experiments the properties of single biomolecules and cells utilizing the instruments of nanotechnology. This change of area was driven by his fascination to the amazing performing of biological molecular structures, along with with the very long-time period standpoint that a lot of exciting discoveries is often envisioned in this field.[5] Present lines of analysis in his biophysics group are inside the regions of:[6]
Your browser isn’t supported any longer. Update it to obtain the very best YouTube working experience and our most current attributes. Find out more
Instance (3) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the movement in the DNA rod is displayed.
We use nanofabricated microfluidic buildings to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which assess the basic function of spatial confinement in the molecular and cellular amount. Our jobs involve the subsequent:
2011, first in vitro measurements of transportation throughout an individual biomimetic nuclear pore sophisticated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the ceesdekker mechanism of homology recognition in DNA homologous recombination
2003, shown the main biosensors designed away from a carbon nanotube; settled the structure and system of DNA repair service proteins; and discovery of a whole new approach for fabricating strong-state nanopores for DNA translocation
Bulk-floor coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro
[14] In 2005 Dekker grew to become involved in Netherlands-extensive conversations about Smart Structure, a movement that he has due to the fact clearly distanced himself from. Dekker advocates that science and faith are not in opposition but might be harmonized.
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker can be an elected member of the KNAW and fellow into the APS plus the IOP.
Allow’s 1st glance again at this time when you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the 1990s.
2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes